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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Chondrogenic induction of human osteoarthritic cartilage-derived mesenchymal stem cells activates mineralization and hypertrophic and osteogenic gene expression through a mechanomiR

Fig. 1

Chondrogenic induction of OASC2 and BMSC. a Comparison of changes in the morphology of OASC2 in chondrogenesis medium (Chondro.) with control (Growth) medium. In chondrogenesis medium, the cells gradually increased in numbers, volume and formed mineral deposition (yellow arrows) by day 14. b Alcian blue staining showed proteoglycans (blue) in OASC2 in chondrogenesis medium (Chondro.) from day 7. c Quantification of Alcian blue staining in OASC2 calculated by ImageJ software. d Alcian blue staining of BMSC in basal medium (Growth) or in chondrogenesis medium (Chondro.). e Quantification of Alcian blue staining in BMSC calculated by ImageJ software. Data are presented as mean ± SD from at least 3 sample images for each group; *p ≤ 0.05; **p ≤ 0.01; ****p ≤ 0.0001, relative to indicated control groups respectively

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