From: Disease activity and damage in juvenile idiopathic arthritis: methotrexate era versus biologic era
Oligoarthritis (n = 238) | Polyarthritis(n = 270) | |||
---|---|---|---|---|
MTX era (n = 102) | Biologic era (n = 136) | MTX era (n = 137) | Biologic era (n = 133) | |
Articular | ||||
Temporomandibular | 7 (6.9) | 10 (7.4) | 16 (11.7) | 13 (9.8) |
Cervical spine | 2 (2.0) | 1 (0.7) | 13 (9.5) | 2 (1.5) |
Shoulder | 1 (1.0) | 0 (0.0) | 14 (10.2) | 1 (0.8) |
Elbow | 3 (2.9) | 1 (0.7) | 27 (19.7) | 1 (0.8) |
Wrist | 2 (2.0) | 0 (0.0) | 31 (22.6) | 2 (1.5) |
Metacarpophalangeal | 1 (1.0) | 1 (0.7) | 15 (10.9) | 3 (2.3) |
Proximal interphalangeal | 2 (2.0) | 0 (0.0) | 29 (21.2) | 5 (3.8) |
Hip | 1 (1.0) | 2 (1.5) | 17 (12.4) | 1 (0.8) |
Knee | 3 (2.9) | 1 (0.7) | 19 (13.9) | 4 (3.0) |
Ankle | 5 (4.9) | 2 (1.5) | 13 (9.5) | 8 (6.0) |
Metatarsophalangeal | 0 (0.0) | 0 (0.0) | 20 (14.6) | 2 (1.5) |
Extraarticular | ||||
Ocular | 13 (12.7) | 1 (0.7) | 8 (5.8) | 6 (4.5) |
Muscular atrophy | 6 (5.9) | 6 (4.4) | 13 (9.5) | 2 (1.5) |
Osteoporosis | 1 (1.0) | 0 (0.0) | 2 (1.5) | 1 (0.8) |
Avascular necrosis | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.8) |
Scoliosis | 6 (5.9) | 4 (2.9) | 11 (8.0) | 1 (0.8) |
Leg length inequality | 9 (8.8) | 15 (11.0) | 9 (6.6) | 6 (4.5) |
Striae rubrae | 0 (0.0) | 0 (0.0) | 3 (2.2) | 1 (0.8) |
Subcutaneous atrophy | 4 (3.9) | 1 (0.7) | 5 (3.6) | 5 (3.8) |
Growth failure | 2 (2.0) | 0 (0.0) | 17 (12.4) | 1 (0.8) |
Pubertal delay | 0 (0.0) | 0 (0.0) | 5 (3.6) | 0 (0.0) |
Diabetes | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Amyloidosis | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Others | 1 (1.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |