Distinct biomarkers for different bones in osteoporosis with rheumatoid arthritis

Table 5 Summary of multivariable regression analysis

Annual BMD change rate	Lumbar	Proximal femur	Distal forearm
Bisphosphonate		↑↑↑	↑
Vitamin D		↑↑	↑
ACPA		↓↓
TRACP-5b			↓↓↓
Homocysteine	↓

↑↑↑, 3 ≦ t < 3.5 and p < 0.05
↑↑, 2.5 ≦ t < 3.0 and p < 0.05
↑, 2 ≦ t < 2.5 and p < 0.05
↓, − 2.5 ≦ t< − 2 and p < 0.05
↓↓, − 3 ≦ t < − 2.5 and p < 0.05
↓↓↓, − 3.5 ≦ t < − 3 and p < 0.05
BMD bone mineral density, ACPA anti-cyclic citrullinated peptide antibody, TRACP-5b tartrate-resistant acid phosphatase 5b

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