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Table 2 All-cause and cause-specific treatment discontinuation according to baseline smoking status, after balancing differences in baseline covariates and accounting for those excluded from the analysis

From: Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis

 

Never smoker

Ex-smoker

Current smoker

All-cause

Reference

0.68 (0.45 to 1.04)

0.79 (0.53 to 1.20)

Infection-related adverse events

Reference

1.03 (0.55 to 1.96)

0.79 (0.40 to 1.54)

Other adverse events

Reference

1.02 (0.50 to 2.07)

0.86 (0.41 to 1.78)

Inefficacy and other reasons

Reference

0.73 (0.39 to 1.37)

1.44 (0.86 to 2.41)

  1. Results shown as hazard ratios (95% confidence interval). Examples of “other reasons” included patient choice and social circumstances