Fig. 3
From: Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis
Performance of urine biomarkers in discriminating ALN patients from ILN patients, CKD patients, and healthy controls. The same urine biomarker data plotted in Fig. 1 were used to generate these plots. The area under the curve (AUC) is shown within each graph, with the following legend describing the statistical significance: ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05. Urinary creatinine-normalized plasmin and TFPI were both able to successfully differentiate ALN patients from ILN patients (row 1) and healthy controls (row 3). Plasmin, TF, and TFPI successfully discriminated ALN patients from the CKD controls (row 2). The combination of plasmin and TFPI improved the discriminatory potential (last column)