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Table 2 KOOS changes between the follow-up visits (T3 and T1) and baseline FAS population

From: Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study

  BCL high dose, mean ± SD BCL low dose, mean ± SD Placebo, mean ± SD
KOOS change at T1 (difference between T1 and baseline) N 49 46 45
Global score 35.2 ± 67.5 18.0 ± 57.6 7.9 ± 60.2
Pain 7.1 ± 17.5 4.8 ± 16.7 3.1 ± 13.9
Symptoms 6.7 ± 15.2 2.9 ± 13.6 1.7 ± 14.6
Function in daily living (ADL) 5.9 ± 19.6 4.0 ± 16.5 1.4 ± 13.2
Function in sport and recreation (sport/rec) 10.5 ± 18.0 4.2 ± 16.7 2.3 ± 15.4
Knee-related quality of life (QoL) 5.6 ± 14.8 3.1 ± 14.9 − 0.2 ± 16.2
KOOS change at T3 (difference between T3 and baseline) N 47 38 40
Global score 56.3 ± 82.6 48. ± 73.1 42.1 ± 66.2
Pain 12.3 ± 19.4 12.8 ± 18.4 10.8 ± 16.5
Symptoms 10.0 ± 16.6 7.4 ± 16.0 7.5 ± 14.7
Function in daily living (ADL) 9.2 ± 19.5 10.3 ± 20.9 7.3 ± 14.6
Function in sport and recreation (sport/rec) 11.1 ± 20.5 9.6 ± 15.3 9.7 ± 17. 8
Knee related quality of life (QoL) 12.4 ± 20.3 9.2 ± 19.3 6.6 ± 16.8