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Table 1 Clinical characteristics of non-SS subjects included in the proteomics analysis

From: Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers

Patient no. Age Gender Anti-SSA* Anti-SSB* Focus score** FI score*** Schirmer test**** Saliva secretion ***** Dry mouth Dry eyes
1 71 F < 1 1 + + + +
2 33 F 0 1 + NT + +
3 48 F 0 0 + + + +
4 65 F 0 2 + + + +
5 39 F 0 0 + + + +
6 44 F 0 0 + + +
7 30 F 0 0 + + +
8 56 F 0 1 + + + +
9 41 F 0 0 + + + +
10 50 F 0 0 + + + +
11 47 F 0 1 + + +
12 64 F < 1 0 + + + +
13 73 F 0 2 + + + +
14 59 F < 1 0 + + + +
15 51 F < 1 + + + +
  1. F female, FI fatty infiltration, NT not tested
  2. *Autoantibody production was assessed by ELISA
  3. **Values are the number of focal infiltrates/4mm2 tissue area containing > 50 mononuclear cells
  4. ***The degree of fatty infiltration was assessed and the sections were scored blindly, where no or little fatty infiltration = 0, moderate = 1, and prominent = 2
  5. ****Values are in mm/5 min; normal flow > 5 mm/5 min. ‘+’ indicates dryness and tear secretion ≤ 5 mm/5 min
  6. *****Values are in ml/15 min; normal flow > 1.5 ml/15 min. ‘+’ indicates dryness and unstimulated whole saliva secretion ≤ 1.5 ml/15 min