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Table 1 Clinical characteristics of non-SS subjects included in the proteomics analysis

From: Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers

Patient no.

Age

Gender

Anti-SSA*

Anti-SSB*

Focus score**

FI score***

Schirmer test****

Saliva secretion *****

Dry mouth

Dry eyes

1

71

F

< 1

1

+

+

+

+

2

33

F

0

1

+

NT

+

+

3

48

F

0

0

+

+

+

+

4

65

F

0

2

+

+

+

+

5

39

F

0

0

+

+

+

+

6

44

F

0

0

+

+

+

7

30

F

0

0

+

+

+

8

56

F

0

1

+

+

+

+

9

41

F

0

0

+

+

+

+

10

50

F

0

0

+

+

+

+

11

47

F

0

1

+

+

+

12

64

F

< 1

0

+

+

+

+

13

73

F

0

2

+

+

+

+

14

59

F

< 1

0

+

+

+

+

15

51

F

< 1

+

+

+

+

  1. F female, FI fatty infiltration, NT not tested
  2. *Autoantibody production was assessed by ELISA
  3. **Values are the number of focal infiltrates/4mm2 tissue area containing > 50 mononuclear cells
  4. ***The degree of fatty infiltration was assessed and the sections were scored blindly, where no or little fatty infiltration = 0, moderate = 1, and prominent = 2
  5. ****Values are in mm/5 min; normal flow > 5 mm/5 min. ‘+’ indicates dryness and tear secretion ≤ 5 mm/5 min
  6. *****Values are in ml/15 min; normal flow > 1.5 ml/15 min. ‘+’ indicates dryness and unstimulated whole saliva secretion ≤ 1.5 ml/15 min