Skip to main content

Table 2 Univariable and multivariable regression analyses of predicting worsening 2 units or more of mSASSS over 2 years

From: Alcohol consumption as a predictor of the progression of spinal structural damage in axial spondyloarthritis: data from the Catholic Axial Spondyloarthritis COhort (CASCO)

  Univariable Model 1* Model 2†
OR 95% CI P OR 95% CI P OR 95% CI P
Age 1.039 1.016, 1.062 0.001 1.025 0.997, 1.054 0.077 1.027 0.999, 1.056 0.061
Male 1.580 0.900, 2.774 0.111     1.477 0.768, 2.840 0.243
Obesity (BMI ≥ 25 kg/m2) 1.074 0.653, 1.764 0.779       
Alcohol drinker 3.748 2.098, 6.694 < 0.001 4.748 2.488, 9.061 < 0.001 4.401 2.287, 8.469 < 0.001
Current smoker 1.317 0.772, 2.248 0.312     1.039 0.567, 1.905 0.900
Uveitis history 1.870 1.155, 3.029 0.011 2.117 1.214, 3.689 0.008 2.119 1.212, 3.704 0.008
Elevated BASDAI (≥ 4) 1.218 0.713, 2.081 0.471       
Very high ASDAS-CRP (> 3.5) 3.232 0.870, 12.015 0.080 3.049 0.760, 12.234 0.116 3.391 0.825, 13.938 0.090
Positive HLA-B27 0.843 0.304, 2.335 0.743       
Mean grade of sacroiliitis 1.554 1.230, 1.963 < 0.001       
Pre-existing syndesmophyte 2.268 1.380, 3.729 < 0.001 1.762 0.956, 3.247 0.069 1.644 0.882, 3.065 0.117
  1. ASDAS Ankylosing Spondylitis Disease Activity Score, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, BMI body mass index, CI confidence interval, CRP C-reactive protein, OR odd ratio
  2. *All variables yielding a P value under 0.1 in univariable logistic regression analysis were included in model 1, except variables showing multicolinearity with other variables
  3. †Multivariable logistic regression analysis was performed by adding gender and smoking status to the variables included in model 1