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Table 3 Univariable and multivariable regression analyses of predicting new syndesmophyte or pre-existing syndesmophyte progression over 2 years

From: Alcohol consumption as a predictor of the progression of spinal structural damage in axial spondyloarthritis: data from the Catholic Axial Spondyloarthritis COhort (CASCO)

 

Univariable

Model 1*

Model 2†

OR

95% CI

P

OR

95% CI

P

OR

95% CI

P

Age

1.036

1.013, 1.059

0.002

1.026

0.998, 1.055

0.073

1.026

0.997, 1.055

0.076

Male

2.119

1.172, 3.833

0.013

2.271

1.163, 4.435

0.016

2.521

1.262, 5.036

0.009

Obesity (BMI ≥ 25 kg/m2)

0.955

0.580, 1.572

0.955

      

Alcohol drinker

2.957

1.637, 5.340

< 0.001

3.219

1.671, 6.201

< 0.001

3.239

1.673, 6.271

< 0.001

Current smoker

1.032

0.606, 1.758

0.908

   

0.776

0.424, 1.418

0.409

Uveitis history

2.061

1.270, 3.343

0.003

2.368

1.364, 4.113

0.002

2.295

1.319, 3.994

0.003

Elevated BASDAI (≥ 4)

1.104

0.646, 1.887

0.717

      

Very high ASDAS-CRP (> 3.5)

4.474

1.203, 16.640

0.025

5.638

1.361, 23.357

0.017

5.536

1.325, 23.136

0.019

Positive HLA-B27

0.610

0.220, 1.690

0.342

      

Mean grade of sacroiliitis

1.497

1.184, 1.892

0.001

      

Pre-existing syndesmophyte

2.057

1.243, 3.406

0.005

1.400

0.746, 2627

0.295

1.410

0.747, 2.662

0.289

  1. ASDAS Ankylosing Spondylitis Disease Activity Score, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, BMI body mass index, CI confidence interval, CRP C-reactive protein, OR odd ratio
  2. *All variables yielding a P value under 0.1 in univariable logistic regression analysis were included in model 1, except variables showing multicolinearity with other variables
  3. †Multivariable logistic regression analysis was performed by adding smoking status to the variables included in model 1
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Arthritis Research & Therapy

ISSN: 1478-6362

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