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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Clinical features of central nervous system infections and experience in differential diagnosis from neuropsychiatric lupus erythematosus in a cohort of 8491 patients with systemic lupus erythematosus

Fig. 3

ROC curve for WBC, PMN, glucose, protein in CSF, and SSS-8. a ROC curve for WBC, PMN, glucose, and protein in CSF with area under the curve (AUC) being 0.88 (95%CI 0.82–0.94), 0.88 (95%CI 0.81–0.94), 0.88(95%CI 0.82–0.93), and 0.80 (95%CI 0.73–0.88), respectively. The cutoff values for these four indexes are 20/μL, 0.5%, 0.905 g/L, and 2.2 mmol/L, respectively. b ROC curve for simplified scoring system with 8 items (SSS-8). AUC is 0.93 (95%CI 0.86–1.00). The cutoff value for distinguishing CNS infections and NPSLE is 4 with a sensitivity of 85.0% and a specificity of 85.0%. c ROC curve for verifying SSS-8 in newly onset suspected CNS infection and NPSLE cases. The AUC is 0.93 (95%CI 0.80–1.00). The sensitivity and specificity are 85.7% and 93.3%, respectively. ROC, receiver operating characteristic; WBC, white blood cell; CSF, cerebrospinal fluid; AUC, area under the curve; NPSLE, neuropsychiatric lupus erythematosus; PMN, polymorphonuclear leukocyte

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Arthritis Research & Therapy

ISSN: 1478-6362

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