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Table 2 A multivariate logistic regression analysis of key points for discriminating CNS infections from NPSLE

From: Clinical features of central nervous system infections and experience in differential diagnosis from neuropsychiatric lupus erythematosus in a cohort of 8491 patients with systemic lupus erythematosus

Variables P value OR 95%CI
SLE disease duration& ≥ 12 months < 0.05 5.2 1.1–24.5
Pulse GCs* 0.070 7.7 0.8–70.7
Fever§ < 0.001 34.3 5.2–226.7
CSF glucose ≤ 2.2 mmol/L§ < 0.01 13.7 2.1–85.8
CSF PMN leukocytosis§ < 0.05 1.10 1.00–1.19
Hypocomplementemia§ < 0.01 0.08 0.02–0.41
  1. CNS central nervous system, NPSLE neuropsychiatric lupus erythematosus, GCs glucocorticoids, CSF cerebrospinal fluid, PMN polymorphonuclear leukocyte
  2. &Disease duration from SLE diagnosis to CNS infections or NPSLE onset
  3. *Evaluated medical history before the diagnosis of CNS infection or NPSLE
  4. §Evaluated within 2 weeks of CNS infection or NPSLE onset
  5. Significant p values are shown in bold typeface