Clinical features of central nervous system infections and experience in differential diagnosis from neuropsychiatric lupus erythematosus in a cohort of 8491 patients with systemic lupus erythematosus

Table 4 Baseline demographics, CNS features, and SSS-8 of seven patients diagnosed with CNS infections

Case	Gender	Age at SLE diagnosis (years)	Disease duration (months)	Neuropsychiatric symptoms	CSF examination					Hypocomplementemia	SSS-8	Possible CNS infections	Final diagnosis	Etiology	Concordance of prejudge with final diagnosis
Case	Gender	Age at SLE diagnosis (years)	Disease duration (months)	Neuropsychiatric symptoms	Pressure (mmH₂O)	WBC (/μL)	PMN ratio (%)	Protein (g/L)	Glucose (mmol/L)	Hypocomplementemia	SSS-8	Possible CNS infections	Final diagnosis	Etiology	Concordance of prejudge with final diagnosis
1	F	35	1	Fever, headache, hemiplegia	310	580	94	1.07	4.23	No	6	Yes	Brain abscess	Listeria monocytogenes	Yes
2	F	37	2	Fever, headache, hemiplegia	260	59	1	0.6	2.8	No	4	Yes	Brain abscess	Unknown	Yes
3	F	54	5	Fever, cognitive dysfunction, consciousness disturbance	135	690	92.4	8.83	0.9	Yes	5	Yes	Meningoencephalitis	Unknown	Yes
4	F	53	1	Fever, headache, vomiting, consciousness disturbance	> 330	269	4.9	2.42	2.7	Yes	5	Yes	Meningitis	Mycobacterium	Yes
5	F	12	3	Fever, headache	160	50	12	1.5	2.0	Yes	5	Yes	Meningitis	Fusarium	Yes
6	F	12	122	Fever, headache, vomiting	120	1054	98	2.78	0.1	No	7	Yes	Meningitis	Gram-negative bacillus	Yes
7	M	26	60	Fever, headache, vomiting, consciousness disturbance	230	6	0	0.45	2.7	Yes	2	No	Brain abscess	Listeria monocytogenes	No

CNS central nervous system, SLE systemic lupus erythematosus, NPSLE neuropsychiatric lupus erythematosus, CSF cerebrospinal fluid, WBCs white blood cells, PMN polymorphonuclear leukocyte, SSS-8 simplified scoring system with 8 items

ISSN: 1478-6362