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Table 4 Baseline demographics, CNS features, and SSS-8 of seven patients diagnosed with CNS infections

From: Clinical features of central nervous system infections and experience in differential diagnosis from neuropsychiatric lupus erythematosus in a cohort of 8491 patients with systemic lupus erythematosus

Case

Gender

Age at SLE diagnosis (years)

Disease duration (months)

Neuropsychiatric symptoms

CSF examination

Hypocomplementemia

SSS-8

Possible CNS infections

Final diagnosis

Etiology

Concordance of prejudge with final diagnosis

Pressure (mmH2O)

WBC (/μL)

PMN ratio (%)

Protein (g/L)

Glucose (mmol/L)

1

F

35

1

Fever, headache, hemiplegia

310

580

94

1.07

4.23

No

6

Yes

Brain abscess

Listeria monocytogenes

Yes

2

F

37

2

Fever, headache, hemiplegia

260

59

1

0.6

2.8

No

4

Yes

Brain abscess

Unknown

Yes

3

F

54

5

Fever, cognitive dysfunction, consciousness disturbance

135

690

92.4

8.83

0.9

Yes

5

Yes

Meningoencephalitis

Unknown

Yes

4

F

53

1

Fever, headache, vomiting, consciousness disturbance

> 330

269

4.9

2.42

2.7

Yes

5

Yes

Meningitis

Mycobacterium

Yes

5

F

12

3

Fever, headache

160

50

12

1.5

2.0

Yes

5

Yes

Meningitis

Fusarium

Yes

6

F

12

122

Fever, headache, vomiting

120

1054

98

2.78

0.1

No

7

Yes

Meningitis

Gram-negative bacillus

Yes

7

M

26

60

Fever, headache, vomiting, consciousness disturbance

230

6

0

0.45

2.7

Yes

2

No

Brain abscess

Listeria monocytogenes

No

  1. CNS central nervous system, SLE systemic lupus erythematosus, NPSLE neuropsychiatric lupus erythematosus, CSF cerebrospinal fluid, WBCs white blood cells, PMN polymorphonuclear leukocyte, SSS-8 simplified scoring system with 8 items