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Fig. 10 | Arthritis Research & Therapy

Fig. 10

From: Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage

Fig. 10

Curcumin alleviates the swelling of ankle and footpad in MSU-induced arthritis. a MSU suspensions were injected into the right rear ankle joints of C57BL/6 mice, while the same volume of PBS was injected into the left ankles. The swelling is expressed as the right-left/left ratio and a ratio > 0.15 indicates inflammation. Data are expressed as the mean ± SEM of six mice per group. b A total of 1 mg/40 μl MSU suspensions were injected into the right footpad of mice, and foot thickness was detected 24 h after MSU administration (n = 6 for each group). c The ankle joint swelling index is expressed as the MSU-injected joint/PBS-injected joint ratio. d The paw swelling index is expressed as the MSU-injected paw/PBS-injected paw ratio. e Myeloperoxidase (MPO) activity of the homogenates of footpad tissue (n = 4 per group, mean ± SEM)

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