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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage

Fig. 7

Curcumin inhibits the activity of T-SOD, Caspase-1 activation, and secretion of IL-1β in the MSU-stimulated RAW264.7 cells. a Effects of curcumin on the MSU-stimulated protein levels of p20 subunit of Caspase-1. b the activity of T-SOD (n = 3, mean ± SEM). c Densitometry analysis of p20 subunit of Caspase-1, the results represent the mean ± SEM for three experiments. P < 0.05. d Supernatants were analyzed by ELISA for IL-1β (n = 3, mean ± SEM). #Significantly different from absence both MSU and curcumin. *Significantly different from absence of curcumin, P < 0.05

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Arthritis Research & Therapy

ISSN: 1478-6362

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