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Table 1 Descriptive statistics

From: Subclinical and clinical atherosclerosis in rheumatoid arthritis: results from the 3-year, multicentre, prospective, observational GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study

Clinical variables

 Participants, number

841

Demographic characteristics

 Age (841 participants), median (range)

60 years (21–90)

 Female gender (841 participants), n (%)

691 (82.2%)

RA-related features

 RF and/or ACPA (841 participants), n (%)

615 (73.1%)

 Disease duration (834 participants), median (range)

8.2 years (0.1–35)

 Extra-articular features (840 participants), n (%)

138 (16.4%)

 Radiographic damage (814 participants), n (%)

383 (47.1%)

 Joint surgery (841 participants), n (%)

101 (12.4%)

 Maintenance of remission (836 participants), n (%)

349 (41.8%)

 CRP (833 participants), mean ± SD

4.31 ± 3.62 mg/L

Traditional CV risk factors

 BMI (829 participants), mean ± SD

27.01 ± 4.02

 HBP (811 participants), n (%)

400 (49.3%)

 High cholesterol (798 participants), n (%)

256 (32.1%)

 Smoking habit (836 participants), n (%)

264 (31.6%)

 MetS (807 participants), n (%)

180 (22.3%)

 T2D (811 participants), n (%)

98 (12.1%)

Therapies

 ASA (838 participants), n (%)

320 (38.2%)

 CCS (841 participants), n (%)

612 (72.8%)

 CCSs low dosage (841 participants), n (%)

504 (60.0%)

 MTX (841 participants), n (%)

716 (85.1%)

 HCQ (813 participants), n (%)

231 (28.5%)

 LEF (841 participants), n (%)

186 (22.1%)

 SSZ (841 participants), n (%)

113 (13.4%)

 Biologic DMARDs (841 participants), n (%)

517 (61.5%)

 TNFi (841 participants), n (%)

308 (36.6%)

 Non TNFi (841 participants), n (%)

209 (24.9%)

  1. Participants with missing data, n (%): disease duration, 7 (0.8%); extra-articular features, 1 (0.1%); radiographic damage, 27 (3.2%); maintenance of remission, 5 (0.6%); CRP, 8 (0.9%); BMI, 12 (1.4%); high cholesterol, 43 (5.1%); HBP, 30 (3.6%); smoking habit, 5 (0.6%); MetS, 34 (4.0%); T2D, 30 (3.6%); ASA, 3 (0.3%); HCQ, 28 (3.3%)
  2. Abbreviations: RA rheumatoid arthritis, RF rheumatoid factor, ACPA Anti-citrullinated protein antibodies, CRP mean values of C reactive protein during the follow-up, SD standard deviation, CV cardiovascular, BMI mean body mass index during the follow-up, MetS metabolic syndrome, HBP high blood pressure, T2D type 2 diabetes, ASA acetylsalicylic acid, aspirin, CCSs corticosteroids, MTX methotrexate, HCQ hydroxychloroquine, SSZ sulfasalazine, LEF leflunomide, TNFi tumour necrosis factor inhibitor