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Table 1 List of 20 overlapped genes identified by TWAS in both MS and YBL for chondropathies

From: Integrating transcriptome-wide study and mRNA expression profiles yields novel insights into the biological mechanism of chondropathies

Gene

Chromosome

P TWAS MS

P TWAS YBL

ACADM

1

3.03 × 10− 2

4.14 × 10− 2

ADIPOR1

1

3.83 × 10− 2

9.15 × 10− 3

AGA

4

4.34 × 10− 2

1.48 × 10− 2

ARMC1

8

1.62 × 10− 3

8.76 × 10− 3

CHURC1

14

1.59 × 10− 2

1.63 × 10− 2

FAM149B1

10

5.03 × 10−3

5.30 × 10− 3

FPGT

1

3.69 × 10−4

1.40 × 10− 2

KHK

2

1.57 × 10−2

1.02 × 10− 2

MTFR1

8

5.32 × 10−3

3.30 × 10−2

NDFIP1

5

7.48 × 10−3

3.82 × 10−2

NDUFA10

2

1.56 × 10−2

6.11 × 10−3

NME6

3

9.93 × 10−3

1.75 × 10−3

NSA2

5

2.47 × 10−4

3.30 × 10−4

NUDT13

10

9.46 × 10−3

2.77 × 10− 3

NUDT2

9

1.85 × 10−2

2.32 × 10− 2

PHLPP2

16

7.58 × 10−3

1.88 × 10−2

RSRC1

3

4.54 × 10−4

1.03 × 10− 4

SH3GLB2

9

1.46 × 10−2

7.00 × 10−3

TAF1B

2

2.85 × 10−2

2.38 × 10−2

TRIM66

11

2.80 × 10−2

2.86 × 10−2

  1. Note: PTWAS MS and PTWAS YBL denote the TWAS P value in muscle skeleton (MS) and peripheral blood (YBL)