|
Autoimmune disease
|
Total
|
Event (%)
|
Total person-years
|
Incidence rate (/105 years)
|
IRR (95% CI)
|
|---|
|
Acute anterior uveitis
|
|
Non-AS
|
307,265
|
420 (0.14)
|
1,233,168
|
34.1
|
Reference
|
|
AS
|
28,335
|
643 (2.13)
|
103,487
|
583.6
|
17.14 (15.13–19.41)
|
|
Psoriasis
|
|
Non-AS
|
307,048
|
508 (0.17)
|
1,231,732
|
41.2
|
Reference
|
|
AS
|
30,240
|
176 (0.58)
|
111,703
|
157.6
|
3.82 (3.22–4.53)
|
|
Inflammatory bowel disease
|
|
Non-AS
|
299,243
|
12 (0.004)
|
1,205,603
|
1.0
|
Reference
|
|
AS
|
29,462
|
9 (0.03)
|
109,791
|
8.2
|
8.24 (3.47–19.55)
|
|
Crohn’s disease
|
|
Non-AS
|
299,776
|
4 (0.001)
|
1,207,612
|
0.3
|
Reference
|
|
AS
|
29,560
|
3 (0.01)
|
110,132
|
2.7
|
8.22 (1.84–36.75)
|
|
Ulcerative colitis
|
|
Non-AS
|
308,500
|
8 (0.003)
|
1,238,652
|
0.6
|
Reference
|
|
AS
|
30,793
|
7 (0.02)
|
114,074
|
6.1
|
9.50 (3.45–26.20)
|
|
Systemic lupus erythematosus
|
|
Non-AS
|
308,500
|
40 (0.01)
|
1,238,580
|
3.2
|
Reference
|
|
AS
|
30,517
|
29 (0.10)
|
113,090
|
25.6
|
88.20 (11.03–705.18)
|
|
Sjögren’s syndrome
|
|
Non-AS
|
306,049
|
80 (0.03)
|
1,230,358
|
6.5
|
Reference
|
|
AS
|
29,772
|
91 (0.31)
|
110,650
|
82.2
|
12.65 (9.37–17.08)
|
|
Rheumatoid arthritis
|
|
Non-AS
|
305,326
|
112 (0.04)
|
1,226,848
|
9.1
|
Reference
|
|
AS
|
27,531
|
190 (0.69)
|
102,233
|
185.9
|
20.36 (16.12–25.71)
|
|
Systemic sclerosis
|
|
Non-AS
|
309,048
|
9 (0.003)
|
1,240,674
|
0.7
|
Reference
|
|
AS
|
30,872
|
8 (0.03)
|
114,346
|
7.0
|
9.64 (3.72–25.00)
|
|
Dermatomyositis
|
|
Non-AS
|
308,846
|
8 (0.003)
|
1,239,911
|
0.6
|
Reference
|
|
AS
|
30,843
|
4 (0.01)
|
114,233
|
3.5
|
5.43 (1.63–18.02)
|
|
Polymyositis
|
|
Non-AS
|
308,832
|
2 (0.001)
|
1,239,818
|
0.2
|
Reference
|
|
AS
|
30,827
|
2 (0.01)
|
114,166
|
1.8
|
10.86 (1.53–77.10)
|
|
Thromboangiitis obliterans
|
|
Non-AS
|
309,093
|
2 (0.001)
|
1,240,854
|
0.2
|
Reference
|
|
AS
|
30,907
|
3 (0.01)
|
114,474
|
2.6
|
16.26 (2.72–97.31)
|
|
Behcet’s disease
|
|
Non-AS
|
309,039
|
4 (0.001)
|
1,240,654
|
0.3
|
Reference
|
|
AS
|
30,820
|
21 (0.07)
|
114,144
|
18.4
|
57.06 (19.59–166.24)
|
|
Pemphigus
|
|
Non-AS
|
309,061
|
4 (0.001)
|
1,240,728
|
0.3
|
Reference
|
|
AS
|
30,906
|
2 (0.01)
|
114,477
|
1.7
|
5.42 (0.99–29.59)
|
|
Sarcoidosis
|
|
Non-AS
|
309,088
|
21 (0.01)
|
1,240,775
|
1.7
|
Reference
|
|
AS
|
30,897
|
16 (0.05)
|
114,402
|
14.0
|
8.26 (4.31–15.84)
|
|
Vitiligo
|
|
Non-AS
|
308,750
|
98 (0.03)
|
1,239,523
|
7.9
|
Reference
|
|
AS
|
30,838
|
21 (0.07)
|
114,251
|
18.4
|
2.32 (1.45–3.72)
|
- Abbreviations: AS ankylosing spondylitis, IRR incidence rate ratio, CI confidence interval
