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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis

Fig. 1

Analysis workflow. Fluorescence signals from a genome-wide SNP array with 2.5 million probes were analyzed to profile CNV in patients with RA. CNVs overlapped across the study subjects were segmented at all CNV boundaries. In the example shown in the figure, CNVs overlapped with different boundaries (determined by fluorescence signals at SNPs) among three subjects were divided into three segments. Different boundaries and SNPs are indicated by dash lines and orange dots, respectively. Associations between CNV segments and response to the treatments were then tested using ΔDAS28 and ΔCDAI

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Arthritis Research & Therapy

ISSN: 1478-6362

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