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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Fig. 5

CCR6+ ILC number is positively correlated with SF CCL20 levels. a Comparison of CCL20 concentration in SF of patients with OA (n = 24) and RA (n = 16). CCL20 concentration in SF of patients with RA was significantly higher than that in SF from OA patients. CCL20 levels in synovial fluid were measured by ELISA. Data was analyzed using the Wilcoxon rank-sum test. (*p < 0.05, **p < 0.01, ***p < 0.001). b The absolute number of CCR6+ ILCs in SF of patients of OA (n = 13) and RA (n = 15). Data was analyzed using the Wilcoxon rank-sum test. (*p < 0.05, **p < 0.01, ***p < 0.001). c Correlation of the number of CCR6+ ILCs and CCL20 concentration in SF of patients with OA (n = 13) and RA (n = 15). The number of CCR6+ ILCs was positively correlated with CCL20 concentration. Data are presented as scatter plots with a linear fit and analyzed by calculating Spearman’s rank correlation coefficient

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