Fig. 4

a Course of FOI sum scores in comparison to EULAR response criteria of “low disease activity” according to DAS28. b Course of FOI sum scores in comparison to EULAR response criteria of “remission” according to DAS28: non-responder (DAS28(ESR) > 3.2), responder (DAS28(ESR) ≤3.2 and improvement of > 0.6). FOI = fluorescence optical imaging; DAS28 = Disease Activity Score of 28 joints. V0 (red): baseline, V12 (blue): follow-up after 12 months