From: Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis
n = 88 | |
---|---|
Age—years | |
Median | 53 |
Range | 22–88 |
Sex—no. (%) | |
Female | 66 (75) |
Male | 22 (25) |
SSc subtype—no. (%) | |
Limited cutaneous SSc | 57 (65) |
Diffuse cutaneous SSc | 31 (35) |
Disease duration—years | |
Median | 8 |
Range | 0–40 |
Erythrocyte sedimentation rate—mm/h | |
Mean | 14 |
Range | 0–94 |
C-reactive protein—mg/dl | |
Mean | 0.4 |
Range | 0.01–2.52 |
Serum gamma globulins—% | |
Mean | 16 |
Range | 9.4–38.3 |
Auto-antibodies—no. (%) | |
Anti-nuclear Ab | 82 (93) |
Anti-Scl-70 | 39 (44) |
Anti-centromere Ab | 24 (27) |
Modified Rodnan skin score (mRSS) | |
Mean | 8 |
Range | 0–44 |
Pretreatment—no. (%) | |
Cyclophosphamide | 23 (26) |
Rituximab | 2 (2) |
Autologous stem cell transplantation | 6 (7) |
Immunosuppressive therapy at blood draw—no. (%) | |
None | 37 (42) |
Prednisolone | 6 (7) |
Cyclophosphamide | 5 (6) |
Mycophenolate | 23 (26) |
Azathioprine | 5 (6) |
Methotrexate | 10 (11) |
Others | 3 (3) |