| Whole population (n = 1065) | High-risk subgroupa (n = 173) |
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Hazard ratio (95% profile likelihood CI) | Hazard ratio (95% profile likelihood CI) |
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Univariable analysis | Multivariable analysisb | Univariable analysis | Multivariable analysisc |
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TMP-SMX prophylaxis | 2.03 (0.02–17.95) | 0.51 (0.004–5.30) | 0.76 (0.006–6.74) | 0.18 (0.001–2.31) |
p value for hazard ratio | 0.661 | 0.627 | 0.850 | 0.216 |
- CI confidence interval, PCP pneumocystis pneumonia, TMP-SMX trimethoprim–sulfamethoxazole
- aDefined as treatment episodes with baseline lymphopenia and/or concomitant steroid-pulse treatment
- bIncluded concomitant steroid pulse and cyclophosphamide, higher previously used steroid (≥ 800 mg of prednisone or equivalent during previous 6 months) and lymphopenia as covariates, and was also adjusted for clustering
- cIncluded old age (≥ 70 years) and concomitant steroid-pulse treatment as covariates and was also adjusted for clustering