Fig. 3

Analysis of baseline differences in gene expression between EULAR-GR and EULAR-NR. a Statistically significant (after BH-FDR correction) differences were observed in C1 (blue), but not in C2 (pink). b Genome-wide correlation of average EULAR-GR–EULAR-NR differences at baseline across both cohorts was positive, but not statistically significant by permutation control. c Baseline EULAR-GR–EULAR-NR differences for a subset of more variable genes show greater positive correlation between two cohorts that is less frequently observed upon permutation and includes cell surface markers for myeloid cells (CD136, CD63) higher on average in EULAR-GR in both cohorts (orange) and lymphocytes (e.g., CD52 and CD22) on average higher in EULAR-NR in both cohorts (blue)