Fig. 4

Cell type-specific gene expression analysis between EULAR-GR and EULAR-NR at baseline. a Volcano plots of genes predominantly expressed in specific cell types in the blood shows that across both cohorts genes specific to monocytes and neutrophils are expressed (on average) higher in EULAR-GR whereas those specific to B cell and T cells are expressed (on average) higher in EULAR-NR. The horizontal line corresponds to a permutation p value of 0.05. b Same analysis was applied to five publicly available datasets. A similar observation was made in three of the five datasets