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Table 2 Multivariate analysesa of predictive value of early MRI changes for later radiographic changes

From: Very early MRI responses to therapy as a predictor of later radiographic progression in early rheumatoid arthritis

  Change from baseline to month 1 Change from baseline to month 3
Change from baseline to month 12   RAMRIQ synovitis RAMRIQ osteitis RAMRIS erosions RAMRIQ synovitis RAMRIQ osteitis RAMRIS erosions
Total radiographic progressionb Estimate 0.0002 0.645 0.777 0.0001 0.867 0.434
p value 0.148 0.002 0.043 0.407 0.001 0.073
Radiographic erosion progression Estimate 0.0001 − 0.043 0.590 0.0001 − 0.001 0.425
p value 0.040 0.705 0.007 0.145 0.996 0.001
Radiographic JSN progression Estimate 0.0000 0.688 0.187 0.0000 0.868 0.009
p value 0.647 < 0.001 0.409 0.907 < 0.001 0.954
  1. aBased on multivariate linear regression analysis
  2. bAssessed by mTSS
  3. JSN joint space narrowing, MRI magnetic resonance imaging, mTSS modified Total Sharp Score, RA rheumatoid arthritis, RAMRIQ automated quantitative RA MRI assessment system, RAMRIS RA MRI scoring system
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Arthritis Research & Therapy

ISSN: 1478-6362

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