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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Potential therapeutic effects of cyanidin-3-O-glucoside on rheumatoid arthritis by relieving inhibition of CD38+ NK cells on Treg cell differentiation

Fig. 4

The effect of CD38+ NK and C3G on MNCs. a Treg cell proportion in MNCs depleted of CD38+ NK cells (CD38+ NK cells (−) MNC). b Cytokine production in medium of cocultured CD38+ NK and MNCs. c IL-10+ Treg proportion in MNCs depleted of CD38+ NK cells. The MNCs were cocultured with CD38+ NK cells following treatment with tumor necrosis factor (TNF)-α, interferon (IFN)-γ, anti-TNF-α, anti-IFN-γ, and C3G. * indicates p < 0.05

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