Fig. 1

Asymptomatic ANA⁺ individuals lacking a SARD diagnosis have just as severe fatigue as UCTD and SARD patients. Shown are scatterplots with results for all subjects and subdivided into those with and without a diagnosis of fibromyalgia. Columns indicate results for ANA⁻ healthy controls (Controls), asymptomatic ANA⁺ individuals (ANS), and patients with UCTD or SARD. Every data point corresponds to an individual subject, with the bars representing the mean with SD. For each set of comparisons, statistical significance was determined using the Kruskal-Wallis test with Dunn’s post-test for multiple comparisons, as compared to controls. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. There were no significant differences between the different ANA⁺ sub-groups