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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Effective treatment of TNFα inhibitors in Chinese patients with Blau syndrome

Fig. 2

Changes in disease activity and inflammatory markers of the patients. Overall, WBC, CRP, ESR, IL-1β, IL-6, VAS, and PGA decreased, and SF-36 increased at the first follow-up of 6 months. TNFα decreased at the first follow-up in patients 2 and 3, but increased in patients 1 and 4. At the last visit of 18 months, WBC, ESR, and CRP remained normal in all except patient 3, whose ESR and CRP increased to above the normal range. Among all the patients, serum levels of IL-1β, TNFα, and IL-6 were higher than those at the first follow-up, except patient 4. For patients 1 and 2, VAS and PGA reduced further at the last follow-up, while for patients 3 and 4, they slightly increased. CRP C-reactive protein, ESR erythrocyte sedimentation rate, VAS visual analogue scale, PGA physician global assessment, SF-36 Short Form-36

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