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Table 1 The characteristics of the patients with ankylosing spondylitis (AS), ulcerative colitis (UC), and healthy controls (HC)

From: A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin

 

AS (n = 150)

UC (n = 18)

HC (n = 17)

Women/men, n (%)

68 (45.3)/82 (54.7)

8 (44.4)/10 (55.6)

6 (35.5)/11 (64.7)

Age, years

55.5 (46–67)

30.5 (27–39)

22 (21–31)

AS symptom duration, years

28.5 (18–39)

  

HLAB27 positive, n (%)

127 (84.7)

  

BAS-G, score

2.8 (1.5–5.9)

  

ASDAS-CRP, score

2.1 (1.3–1.7)

  

BASDAI, score

3.2 (1.8–5.2)

  

BASFI, score

2.3 (1.1–4.1)

  

BASMI, score

3.4 (2.4–4.6)

  

ESR, mm/h

8 (4–14)

  

CRP, mg/L

3 (1–6)

5 (3.5–16.5)

1 (1–1)

Fecal calprotectin, mg/kg

80 (0–190)

606 (29–10,320)

All < 15

Patients on NSAIDs, n (%)

115 (76.7)

0

0

 - Daily use of NSAIDs

61 (40.7)

  

 - On-demand use of NSAIDs

54 (36.0)

  

On TNFi all, n (%)

35 (23.3)

0

N.A.

 - TNFi in monotherapy

16 (10.7)

  

 - TNFi + methotrexate

19 (12.7)

  

On DMARD monotherapy

16 (10.7)

0

N.A.

 - Methotrexate

9 (6.0)

  

 - Sulfasalazine

7 (4.7)

  
  1. Data is presented as median (interquartile range) or number (%)
  2. ASDAS-CRP Ankylosing Spondylitis Disease Activity Score based on CRP, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, BAS-G Bath Ankylosing Spondylitis patient Global score, BASFI Bath Ankylosing Spondylitis Functional Index, BASMI Bath Ankylosing Spondylitis Metrology Index, CRP C-reactive protein, DMARD disease modifying anti-rheumatic drug, ESR erythrocyte sedimentation rate, NSAID non-steroidal anti-inflammatory drug, TNFi tumor necrosis factor inhibitor