Golimumab (N = 2843) | Infliximab (n = 5174) | SMD | |
---|---|---|---|
Physician-specific factors | |||
Female sex | 679 (23.9%) | 1368 (26.4%) | 0.06 |
Age in years, mean (STD) | 52.74 (9.43) | 51.40 (9.29) | 0.14 |
Years in practice | 20.75 (10.86) | 18.68 (10.81) | 0.19 |
Ownership of infusion center | 2528 (88.9%) | 4162 (80.4%) | 0.24 |
Office-based practice** | 2230 (78.4%) | 3906 (75.5%) | 0.07 |
Type of employment | |||
Federal government | 108 (3.8%) | 185 (3.6%) | 0.01 |
Group practice | 1298 (45.7%) | 2237 (43.2%) | 0.05 |
Local government | 180 (6.3%) | 409 (7.9%) | 0.06 |
Medical school | 79 (2.8%) | 110 (2.1%) | 0.04 |
Other | 567 (19.9%) | 1187 (22.9%) | 0.07 |
Solo practice | 611 (21.5%) | 1046 (20.2%) | 0.03 |
Patient-specific factors | |||
Demographics | |||
Age in years, mean (STD) | 70.01 (8.90) | 68.66 (9.47) | 0.15 |
Female | 2287 (80.4%) | 3988 (77.1%) | 0.08 |
White | 2349 (82.6%) | 4233 (81.8%) | 0.02 |
Dual eligible for Medicare and Medicaid | 348 (12.2%) | 886 (17.1%) | 0.14 |
Disability according to Medicare as original reason for Medicare eligibility | 1004 (35.3%) | 1676 (32.4%) | 0.06 |
Comorbidity diagnoses, % | |||
Myocardial infarction | 137 (4.8%) | 226 (4.4%) | 0.02 |
Coronary heart disease | 554 (19.5%) | 977 (18.9%) | 0.02 |
Peripheral vascular disease | 217 (7.6%) | 389 (7.5%) | 0.00 |
Chronic pulmonary disease | 771 (27.1%) | 1359 (26.3%) | 0.02 |
Peptic ulcer disease | 52 (1.8%) | 86 (1.7%) | 0.01 |
Diabetes | 658 (23.1%) | 1168 (22.6%) | 0.01 |
Renal disease | 287 (10.1%) | 462 (8.9%) | 0.04 |
Malignancy | 195 (6.9%) | 331 (6.4%) | 0.02 |
Fibromyalgia | 591 (20.8%) | 978 (18.9%) | 0.05 |
RA and other medications, % | |||
Methotrexate | 1642 (57.8%) | 3595 (69.5%) | 0.25 |
Other conventional DMARDS | 1085 (38.2%) | 2386 (46.1%) | 0.16 |
Oral glucocorticoids | 2039 (71.7%) | 3914 (75.6%) | 0.09 |
NSAIDs | 1299 (45.7%) | 2453 (47.4%) | 0.03 |
Opioid | 2030 (71.4%) | 3585 (69.3%) | 0.05 |
Statin | 1315 (46.3%) | 2219 (42.9%) | 0.07 |
Other lipid lowering drug | 257 (9.0%) | 418 (8.1%) | 0.03 |
Anti-hypertensive drug | 2202 (77.5%) | 3822 (73.9%) | 0.08 |
Anti-depressant drug use | 1283 (45.1%) | 2181 (42.2%) | 0.06 |
Healthcare utilization | |||
Number of physician visits, Mean (STD) | 17.89 (9.35) | 16.96 (9.17) | 0.10 |
Any hospitalization | 604 (21.2%) | 1027 (19.8%) | 0.03 |
Colon cancer screening | 442 (15.5%) | 931 (18.0%) | 0.07 |
Breast cancer screening | 1197 (42.1%) | 2097 (40.5%) | 0.03 |