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Table 1 Take home messages

From: Anti-TNF-alpha-induced lupus

- Know that anti-TNF drugs are the first cause of drug-induced lupus.

- Do a reference assay of ANA and anti-DNA before starting an anti-TNF.

- Do not monitor these rates in the absence of clinical signs.

- The presence of ANA before treatment does not contraindicate treatment.

- Evoke induced lupus in front of a compatible chronology plus clinical signs and autoantibodies.

- Do not diagnose induced lupus on isolated skin damage in an autoimmune context: a “simple” rash or arthralgia with anti-DNA is not sufficient for diagnosis.

- Always think about looking for visceral signs.

- Stop the product in case of induced lupus and do not take another anti-TNF agent but change class.