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Table 2 Oral manifestations and mortality during the follow-up period

From: The effect of pilocarpine on dental caries in patients with primary Sjögren’s syndrome: a database prospective cohort study

VariablePilocarpine (n = 1014)Non-user (n = 2028)p
First dental caries visit
 Event number, n (%)487 (48.0)1047 (51.6) 
 Incidence density (95% CI)§27.4 (25.0–29.9)30.5 (28.7–32.4) 
 Hazard ratio (95% CI)0.93 (0.82, 1.06)Reference0.283
Annual number of dentist visiting for dental caries
 Annual number (mean ± SD)0.70 ± 1.110.75 ± 1.18 
 Rate ratio (95% CI)0.95 (0.85, 1.07)Reference0.433
First periodontitis visit
 Event number, n (%)599 (59.1)1248 (61.5) 
 Incidence density (95% CI)§39.1 (35.9–42.2)41.8 (39.5–44.1) 
 Hazard ratio (95% CI)0.91 (0.81, 1.03)Reference0.124
Annual number of dentist visiting for periodontitis
 Annual number (mean ± SD)0.78 ± 1.060.80 ± 1.07 
 Rate ratio (95% CI)1.004 (0.90, 1.11)Reference0.942
First oral candidiasis
 Event number, n (%)27 (2.7)48 (2.4) 
 Incidence density (95% CI)§1.02 (0.64–1.40)0.91 (0.65–1.17) 
 Hazard ratio (95% CI)1.16 (0.70, 1.94)Reference0.565
  1. CI confidence interval, SD standard deviation;
  2. §Incidence density: number of events per 100 person-years