Skip to main content

Table 4 Odds ratios for incident RA, overall and by serologic phenotype determined by medical record review from clinical testing at diagnosis, using conditional logistic regression in the Nurses’ Health Studies

From: Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis

 OR (95%CI) adjusted for matching factorsaMultivariableb OR (95%CI)
All RA
n = 284 outcomes from total n = 1133
 No asthma1.00 (Ref)1.00 (Ref)
 Asthma1.55 (0.98, 2.45)1.45 (0.91, 2.31)
Seropositive RA
n = 177 outcomes from total n = 706
 No asthma1.00 (Ref)1.00 (Ref)
 Asthma1.94 (1.10, 3.40)1.79 (1.01, 3.18)
Seronegative RA
n = 107 outcomes from total n = 427
 No asthma1.00 (Ref)1.00 (Ref)
 Asthma1.00 (0.44, 2.27)0.97 (0.43, 2.21)
  1. CI confidence interval, OR odds ratio, RA rheumatoid arthritis
  2. aCases and controls were matched by age at index date, time from blood draw to index date, cohort, calendar year, fasting status, menopausal status, and postmenopausal hormone use
  3. bAdditionally adjusted for smoking (continuous pack-years), parental passive smoking (yes/no), ever lived with smoker (yes/no), and body mass index (continuous, kg/m2)