Fig. 4

Inflammatory cell infiltration was alleviated in the kidneys of ALW-treated MRL/lpr mice. a Representative images of CD3, B220, and Iba-1 staining are shown. b Semiquantitative scores of CD3 were determined separately in the glomerular, perivascular, and interstitial areas, showing a significant decrease in these areas of ALW-treated mice. c Sections of B220 staining were scored similarly, demonstrating a marked decrease in the perivascular regions of ALW-treated mice, but not in the glomerular and interstitial areas. d Semiquantitative scores of Iba-1 showed less infiltration of macrophages in the glomerular, perivascular, and interstitial areas in the mice of the ALW group. Scale bar = 50 μm. *p < 0.05, **p < 0.01, ***p < 0.001