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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone

Fig. 5

Triggers of Wnt/β-catenin signaling in SFZ cells. a mRNA levels of Wnt ligands in SFZ cells. b mRNA levels of Prg4, Ctnnb1, Axin2, and Wnt ligands in SFZ cells loaded with cyclic tensile strain. c mRNA levels of Prg4, Ctnnb1, and Axin2 in SFZ cells treated with 100 ng/ml recombinant human (rh) WNT5A, WNT5B, WNT9A, or vehicle for 1 week. All data are expressed as mean ± SD of three biologically independent samples per group. *P < 0.05 and **P < 0.01 versus vehicle or 0 h (one-way ANOVA followed by Tukey’s correction)

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