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Fig. 8 | Arthritis Research & Therapy

Fig. 8

From: LNA-anti-miR-150 ameliorated kidney injury of lupus nephritis by inhibiting renal fibrosis and macrophage infiltration

Fig. 8

Schematic mechanism model of renal protective role of LNA-anti-miR-150. Renal miR-150 increased in lupus nephritis (LN). Renal protective roles of LNA-anti-miR-150 in LN might be mediated by three possible pathways: (1) direct anti-fibrotic role of SOCS1, (2) direct inhibition of macrophages infiltration, and (3) inhibition of renal macrophage filtration through increasing SOCS1

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