Fig. 4

Prediction of locomotor and sensory deficits using the arthritis sensory and motor (ArthriSM) scale. a Correlation of the latency before paw withdrawal (thermal hyperalgesia) with the clinical score (n = 775 pairs). b Correlation of the distance traveled (global locomotion; open field test) with the clinical score (n = 375 pairs). c Correlation of the print area (gait analysis with Catwalk™) with the clinical score (n = 444 pairs). Linear regression equations, Spearman’s correlation coefficient r, and statistical significance (p value) are indicated in each graph. d ArthriSM scale. Relative functional deficits for the three assessed functional parameters are plotted according to the percentage of the maximal clinical score. The linear equations are noted for each curve. Data were pooled for all experimental groups and from three independent experiments