Fig. 7From: Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis painProtective effect of m-PGA- on MIA-induced histologic damage. Representative images of H/E-stained sections. Rat knee joints injected with MIA showed a significant expansion of the synovial membrane probably caused by proteinaceous edema fluid and fibrin with infiltrating macrophages, plasma cells, lymphocytes, and neutrophils (b) compared to control (a). Following PGA (c) and even more so by m-PGA (d), synovial membrane expansion and cellular infiltrate still present to a lesser degree. Dotted boxes indicate the region of interestBack to article page