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Fig. 9 | Arthritis Research & Therapy

Fig. 9

From: Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

Fig. 9

Effect of m-PGA on MIA-induced collagen changes (Masson trichrome stain). After MIA injection, the knee joint presented cartilage surface fibrillation and thinning, with decreased collagen content (blue staining) and cleft formation, as well as fattened subchondral plate, massive subchondral sclerosis, and a more disoriented trabecular bone structure (b) compared to control (a). PGA (c) and m-PGA (d) counteracted these changes, as also evidenced by the increased and more organized blue staining

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Arthritis Research & Therapy

ISSN: 1478-6362

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