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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity

Fig. 6

ELISA assays showed elevated anti-collagen III, IV, and V antibodies (a) and immunofluorescence assays showed a higher levels of antinuclear antibodies (ANA) (b) in the serum from the mice immunized with Col V. The immunofluorescence shows ANA with a fine dotted and/or Golgi cytoplasmic pattern in serum from C57BL/6 mice immunized with Col V (b, arrow). Data represent the mean ± s.e. (n = 38). P < 0.05

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