Table 5 Percent changes in median (mean) antibody levels in sera and corresponding IC during 24-month follow-up

dsDNA

− 21.4

< 0.001

− 18.2

0.008

− 34.4

< 0.001

− 25.0

0.049

− 32.3

< 0.001

− 40.3

0.044

− 34.9

0.022

− 36.4

0.002

(− 17.2)

n = 41

(− 6.6)

n = 41

(− 27.1)

n = 35

(6.2)

n = 35

(62.7)

n = 30

(1.7)

n = 30

(− 24.8)

n = 22

(− 28.2)

n = 21

Histone

− 23.1

< 0.001

0

0.414

− 26.1

< 0.001

0

0.687

−24.8

0.1051

−17.9

0.595

−23.6

0.411

− 13.9

0.015

(− 17.2)

n = 41

(95.4)

n = 41

(5.5)

n = 35

(15.6)

n = 34

(64.9)

n = 30

(23.3)

n = 29

(4.4)

n = 22

(− 6.5)

n = 21

Ribosomal P

− 20.0

< 0.001

0

0.993

− 31.2

< 0.001

3.33

0.841

− 36.5

< 0.001

− 26.9

0.105

− 41.8

0.001

− 15.9

0.933

(− 13.6)

n = 41

(49.5)

n = 38

(− 32.4)

n = 35

(25.2)

n = 32

(− 28.7)

n = 30

(1.9)

n = 28

(− 30.8)

n = 22

(40.6)

n = 21

PCNA

−26.0

< 0.001

−11.2

0.091

−31.5

< 0.001

2.6

0.773

−30.2

< 0.001

2.2

0.442

−36.1

< 0.001

−31.1

0.006

(− 19.0)

n = 41

(− 3.0)

n = 41

(− 24.6)

n = 35

(22.3)

n = 35

(− 10.3)

n = 30

(15.1)

n = 30

(− 35.6)

n = 22

(− 17.3)

n = 21

SSA/Ro60

− 2.8

0.034

− 1.4

0.222

− 7.1

0.0115

− 7.1

0.599

− 7.0

0.048

− 21.7

0.211

− 6.1

0.0575

− 33.0

0.007

(− 8.6)

n = 41

(1.3)

n = 41

(− 9.3)

n = 35

(30.2)

n = 35

(10.2)

n = 30

(8.1)

n = 30

(28.9)

n = 22

(− 6.5)

n = 21

SSB/La

− 11.9

< 0.001

− 14.3

0.274

− 14.9

0.008

− 7.7

0.053

− 24.9

0.008

− 20.8

0.051

− 27.7

0.041

− 14.2

0.143

(− 11.0)

n = 41

(9.0)

n = 41

(− 13.1)

n = 35

(16.3)

n = 35

(54.2)

n = 30

(9.4)

n = 30

(− 23.7)

n = 22

(23.0)

n = 21

SSA/Ro52

− 9.3

0.1787

− 14.3

0.124

− 6.8

0.474

− 3.5

0.315

− 3.8

0.078

− 15.5

0.292

− 10.6

< 0.001

− 28.2

0.005

(− 6.8)

n = 41

(− 4.7)

n = 41

(− 7.7)

n = 35

(22.7)

n = 35

(− 6.7)

n = 30

(8.9)

n = 30

(− 20.4)

n = 22

(− 11.8)

n = 21

Sm

− 25.0

< 0.001

0

0.406

− 16.7

0.005

0

0.813

− 12.8

0.228

− 27.3

0.292

− 30.0

0.0532

− 40.9

0.050

(− 24.6)

n = 41

(0.1)

n = 33

(− 18.0)

n = 35

(2.0)

n = 31

(17.7)

n = 30

(− 12.0)

n = 28

(− 1.5)

n = 22

(− 26.6)

n = 18

U1RNP

− 13.8

0.0001

− 12.5

0.111

− 13.3

0.010

− 16.7

0.167

− 12.3

0.006

− 26.6

0.001

− 22.8

< 0.001

− 26.3

< 0.001

(− 4.4)

n = 41

(4.4)

n = 41

(3.4)

n = 35

(2.2)

n = 35

(17.5)

n = 30

(3.8)

n = 30

(− 19.3)

n = 22

(− 24.4)

n = 21

Sm-U1RNP

− 14.7

< 0.001

0

0.621

− 15.2

< 0.001

− 14.3

0.137

− 22.4

0.009

− 33.2

0.019

− 31.5

< 0.001

− 25.0

0.007

(− 17.4)

n = 41

(7.4)

n = 40

(− 15.7)

n = 35

(0.8)

n = 34

(11.1)

n = 30

(4.9)

n = 30

(− 25.5)

n = 22

(− 9.2)

n = 21