Table 2 Clinical parameters (maximum mouth’s opening, distance between upper and lower incisors, inter-commissural distance, upper and lower lip’s thickness), expressed as mean ± SD at baseline (T0), during the third injection (T1), the 1-month follow-up (T2), the 3-month follow-up (T3), and the 24-month follow-up (T4)
Baseline (T0) | 1 month (T1) | 2 months (T2) | 3 months (T3) | 24 months (T4) | Comparison to the baseline | ANOVA | Friedman test | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | p value | F | p value | Test Stat. Appr. | p value | ||
T0/T3 | T0/T4 | ||||||||||
Maximum mouth’s opening (mm) | 47.61 (4.56) | 50.91 (6.47) | 50.35 (6.19) | 49.23 (5.27) | 48.60 (5.30) | 0.0059 | 0.0093 | 11.48 | 0.0015 | 30.45 | < 0.0001 |
Distance between upper and lower incisors (mm) | 27.05 (5.80) | 30.65 (5.71) | 30.41 (5.90) | 29.03 (5.65) | 28.14 (5.61) | 0.0051 | 0.0069 | 22.36 | < 0.0001 | 33.04 | < 0.0001 |
Inter-commissural distance (mm) | 49.12 (1.55) | 51.54 (3.01) | 53.43 (2.79) | 51.44 (2.47) | 50.31 (2.02) | 0.0058 | 0.0065 | 23.68 | < 0.0001 | 32.50 | < 0.0001 |
Upper lip’s thickness (mm) | 4.20 (1.54) | 5.25 (1.62) | 5.65 (1.52) | 4.75 (1.35) | 4.45 (1.32) | 0.0154 | 0.15 | 19.64 | < 0.0001 | 29.52 | < 0.0001 |
Lower lip’s thickness (mm) | 3.80 (1.87) | 5.10 (2.13) | 5.75 (1.87) | 4.85 (1.81) | 4.25 (1.85) | 0.0041 | 0.0163 | 22.98 | < 0.0001 | 31.15 | < 0.0001 |