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Table 4 Association of body mass index and change in body mass index with loss of tibial cartilage volume over 10.7 years (n = 428)

From: Association of age, sex and BMI with the rate of change in tibial cartilage volume: a 10.7-year longitudinal cohort study

 Multivariable, β (95% CI)Multivariable, β (95% CI)
BMI at baselineBMI at baselineChange in BMI
Loss of cartilage volume (mm3/year)
 Medial tibial0.55 (0.27 to 0.84)0.58 (0.29 to 0.86)0.85 (0.26 to 1.43)
 Lateral tibial0.12 (− 0.15 to 0.40)0.14 (− 0.14 to 0.42)0.38 (− 0.20 to 0.95)
 Total tibial0.69 (0.27 to 1.12)0.73 (0.31 to 1.15)1.20 (0.33 to 2.07)
Loss of cartilage volume (%/year)
 Medial tibial0.038 (0.020 to 0.056)0.040 (0.022 to 0.058)0.055 (0.018 to 0.093)
 Lateral tibial0.008 (− 0.005 to 0.022)0.009 (− 0.005 to 0.023)0.022 (− 0.007 to 0.050)
 Total tibial0.022 (0.011 to 0.034)0.023 (0.012 to 0.035)0.035 (0.010 to 0.059)
  1. Model 1: adjusted for age, sex, radiographic osteoarthritis, history of knee surgery and knee injury, physical activity and site-specific tibial cartilage volume at baseline
  2. Model 1 + change in BMI over 10.7 years
  3. Italicised data denotes statistically significant results. BMI body mass index, CI confidence interval