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Table 4 Association of body mass index and change in body mass index with loss of tibial cartilage volume over 10.7 years (n = 428)

From: Association of age, sex and BMI with the rate of change in tibial cartilage volume: a 10.7-year longitudinal cohort study

 

Multivariable, β (95% CI)

Multivariable, β (95% CI)

BMI at baseline†

BMI at baseline‡

Change in BMI‡

Loss of cartilage volume (mm3/year)

 Medial tibial

0.55 (0.27 to 0.84)

0.58 (0.29 to 0.86)

0.85 (0.26 to 1.43)

 Lateral tibial

0.12 (− 0.15 to 0.40)

0.14 (− 0.14 to 0.42)

0.38 (− 0.20 to 0.95)

 Total tibial

0.69 (0.27 to 1.12)

0.73 (0.31 to 1.15)

1.20 (0.33 to 2.07)

Loss of cartilage volume (%/year)

 Medial tibial

0.038 (0.020 to 0.056)

0.040 (0.022 to 0.058)

0.055 (0.018 to 0.093)

 Lateral tibial

0.008 (− 0.005 to 0.022)

0.009 (− 0.005 to 0.023)

0.022 (− 0.007 to 0.050)

 Total tibial

0.022 (0.011 to 0.034)

0.023 (0.012 to 0.035)

0.035 (0.010 to 0.059)

  1. †Model 1: adjusted for age, sex, radiographic osteoarthritis, history of knee surgery and knee injury, physical activity and site-specific tibial cartilage volume at baseline
  2. ‡Model 1 + change in BMI over 10.7 years
  3. Italicised data denotes statistically significant results. BMI body mass index, CI confidence interval