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Table 1 Demographic characteristics and laboratory measurements of the studied subjects

From: Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis

 HC (n = 497)SLE (n = 905)LNA (n = 334)LNI (n = 255)Fχ2P
Demographic characteristics
 Male, n (%)260 (52)57 (6)36 (12)32 (13)  
 Female, n (%)237 (48)848 (94)298 (88)223 (87)  
 Age (years)46.2 (11~85)39.2 (13~82)38.44 (13~76)40.3 (13~80)  
Laboratory measurements
 UACR (mg/g), M (P25, P75)8.15 (4.52,10.7)9.31 (4.43, 12.07)1197.00 (557.49,2212.39)131.73 (57.01, 220.48)  
 Urinary protein (g/24 h), M (P25, P75)0.08 (0.04, 0.11)0.14 (0.09, 0.20)2.47 (0.95, 3.43)0.18 (0.08, 0.27)  
 Creat (μmol/L)65.2 ± 12.9755.1 ± 11.44a62.2 (50.7, 87.4)b61.2 ± 23.25abc217.8340.000
 Urea (mmol/L)5.11 ± 1.174.93 ± 1.58a6.15 (4.58,8.88)ab5.74 ± 2.17bc131.7280.000
 Urea/Creat0.08 ± 0.020.09 ± 0.03a0.10 ± 0.04ab0.10 ± 0.03ab29.6570.000
 CysC (mg/L)0.80 ± 0.130.96 ± 0.23a1.22 (1.01, 1.75)ab1.09 ± 0.41abc550.6240.000
 eGFRCysC [mL/(min·1.73 m2)]100.3 ± 16.3385.5 ± 17.12a62.9 ± 23.92ab78.5 ± 18.68abc283.3280.000
 eGFRCreat [mL/(min·1.73 m2)]121.0 ± 24.37139.9 ± 36.67a112.7 ± 52.76ab131.6 ± 40.82abc52.8860.000
 C1q (mg/L)182.29 ± 28.91170.58 ± 35.52a153.24 ± 39.57ab170.80 ± 36.16ac46.3300.000
  1. CysC and C1q were measured by turbidimetric immunoassay, and Urea and Creat were detected by the urease method and sarcosine oxidase assay, respectively. ANOVA analysis or Kruskal-Wallis test was used for comparing the differences among the multiple groups. Fχ2 and P represented the statistical results of ANOVA analysis or Kruskal-Wallis test among all the study groups
  2. Urea urea, Creat creatinine, CysC cystatin C, C1q complement component 1q, UACR urinary albumin to creatinine ratio
  3. aCompared with the HC group, P < 0.05
  4. bCompared with the SLE group, P < 0.05
  5. cCompared with the LNA group, P < 0.05