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Table 4 Diagnostic efficiency of the individual biomarker of LNA

From: Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis

ItemsAUC (95% CI)Z/PaCutoff VSe (%)Sp (%)YIZ/Pb
Creat0.508 (0.473~0.542)0.346/0.72990.176.030.00.20913.816/0.000
eGFRCreat0.539 (0.504~0.573)1.731/0.08479.6525.198.00.23118.447/0.000
Urea/Creat0.639 (0.605~0.672)6.836/0.0000.0955.468.40.23811.141/0.000
Urea0.668 (0.634~0.700)8.144/0.0006.4046.186.50.32611.976/0.000
C1q0.753 (0.723~0.782)13.753/0.00014449.194.40.4357.015/0.000
CysC0.906 (0.884~0.925)35.891/0.0001.0075.794.60.703
eGFRCysC0.907 (0.885~0.926)36.100/0.00077.8975.794.60.703
  1. Receiver operating characteristic (ROC) curve was applied to identify the diagnostic efficiencies of individual indicator. Z was the statistics of DeLong non-parametric test to evaluate the statistical difference between the two AUCs
  2. Creat creatinine, Urea urea, C1q complement component 1q, CysC cystatin C
  3. aZ and P values were the AUC-based statistics of each item
  4. bZ and P values were the AUC-based statistics of each item in comparison with eGFRCysC