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Table 4 Diagnostic efficiency of the individual biomarker of LNA

From: Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis

Items

AUC (95% CI)

Z/Pa

Cutoff V

Se (%)

Sp (%)

YI

Z/Pb

Creat

0.508 (0.473~0.542)

0.346/0.729

90.1

76.0

30.0

0.209

13.816/0.000

eGFRCreat

0.539 (0.504~0.573)

1.731/0.084

79.65

25.1

98.0

0.231

18.447/0.000

Urea/Creat

0.639 (0.605~0.672)

6.836/0.000

0.09

55.4

68.4

0.238

11.141/0.000

Urea

0.668 (0.634~0.700)

8.144/0.000

6.40

46.1

86.5

0.326

11.976/0.000

C1q

0.753 (0.723~0.782)

13.753/0.000

144

49.1

94.4

0.435

7.015/0.000

CysC

0.906 (0.884~0.925)

35.891/0.000

1.00

75.7

94.6

0.703

–

eGFRCysC

0.907 (0.885~0.926)

36.100/0.000

77.89

75.7

94.6

0.703

–

  1. Receiver operating characteristic (ROC) curve was applied to identify the diagnostic efficiencies of individual indicator. Z was the statistics of DeLong non-parametric test to evaluate the statistical difference between the two AUCs
  2. Creat creatinine, Urea urea, C1q complement component 1q, CysC cystatin C
  3. aZ and P values were the AUC-based statistics of each item
  4. bZ and P values were the AUC-based statistics of each item in comparison with eGFRCysC