Table 5 Diagnostic efficiencies of combined biomarkers of LNA
From: Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis
Items | AUC (95%CI) | Z/Pa | Se (%) | Sp (%) | YI | Z/Pb |
|---|---|---|---|---|---|---|
C1q + eGFRCreat | 0.756 (0.725~0.785) | 13.926/0.000 | 51.2 | 92.2 | 0.434 | 12.196/0.000 |
C1q + Creat | 0.765 (0.735~0.794) | 4.587/0.000 | 57.5 | 88.9 | 0.464 | 11.864/0.000 |
C1q + Urea | 0.805 (0.776~0.831) | 18.108/0.000 | 62.0 | 89.9 | 0.519 | 10.627/0.000 |
C1q + CysC | 0.933 (0.914~0.949) | 46.787/0.000 | 82.9 | 92.6 | 0.755 | 6.172/0.000 |
C1q + Urea + eGFRCreat | 0.813 (0.785~0.839) | 8.969/0.000 | 70.7 | 81.7 | 0.524 | 10.309/0.000 |
C1q + Urea + CysC | 0.934 (0.915~0.950) | 46.787/0.000 | 82.9 | 92.6 | 0.755 | 6.182/0.000 |
Urea + CysC + eGFRCreat | 0.959 (0.943~0.971) | 67.443/0.000 | 87.7 | 93.2 | 0.809 | 4.178/0.000 |
C1q + CysC + eGFRCreat | 0.969 (0.955~0.980) | 79.306/0.000 | 92.8 | 90.7 | 0.836 | 3.802/0.001 |
Urea + CysC + eGFRCreat + Creat | 0.964 (0.949~0.976) | 73.979/0.000 | 90.4 | 91.8 | 0.822 | 3.053/0.002 |
C1q + Urea + CysC + eGFRCreat | 0.969 (0.955~0.980) | 79.306/0.000 | 92.8 | 90.7 | 0.836 | 3.897/0.001 |
C1q + CysC + eGFRCreat + Creat | 0.974 (0.961~0.984) | 88.822/0.000 | 91.0 | 95.0 | 0.860 | 1.016/0.310 |
C1q + Urea + CysC + eGFRCreat + Creat | 0.975 (0.962~0.984) | 88.976/0.000 | 92.5 | 94.4 | 0.869 | ― |