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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: High-throughput sequencing of CD4+ T cell repertoire reveals disease-specific signatures in IgG4-related disease

Fig. 6

IgG4-RD-specific clusters revealed by CDR3 similarity networks. a CDR3 similarity networks constructed by all the CDR3 amino acid clonotypes expanded in at least one individual. Each two CDR3 amino acid clonotypes with a Levenshtein distance of 1 were connected with each other. Node sizes correspond to the expansion levels of the clonotypes. If the clonotypes were expressed by more than one individual, the node sizes were determined by the highest expansion level. b IgG4-RD-specific clusters and the CDR3 amino acid sequences, source individuals, and expansion levels of each node in the clusters

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