Fig. 6From: Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritisEffect of PlGF-2123-144-α-TNF in joint destruction of the arthritis model. Arthritis was induced by intraperitoneal injection of anti-collagen antibodies, followed by intraperitoneal injection of LPS. On the day of LPS injection, PlGF-2123-144-α-TNF (0.1 μg) was subcutaneously injected into the left hind paw of the CAIA mice. a Arthritis scores of the treated paw represent the mean ± SE from 4 mice. b Representative H&E image of joints on day 9 in the untreated control (left) and PlGF-2123-144-α-TNF-treated group (right). Arrows indicate cellular infiltrations. Scale bars, 200 μmBack to article page