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Table 5 The financial cost of healthcare utilization in SSc by DU severity*

From: Digital ulcers in systemic sclerosis: their epidemiology, clinical characteristics, and associated clinical and economic burden

Healthcare costMild DU*Moderate DU*Severe DU*p value
Mean ± SD, median (25th–75th) or n(%)Mean ± SD, median (25th–75th) or n(%)Mean ± SD, median (25th–75th) or n(%)
Total healthcare cost
 Total cost/pt. (2008–2015)45,933 (24,823–99,604)48,199 (30,472–79,802)79,827 (36,861–117,822)0.44
 Median annual cost/pt.8269 (5784–11,713)7881 (6220–11,433)9048 (5429–10,700)0.46
Hospital cost
 Total cost/pt. (2008–2015)25,317 (7039–74,211)33,783 (7573–58,526)51,567 (15,752–98,245)0.29
 Median annual cost/ pt4232 (2716–6843)4297 (2963–6207)4614 (2889–6978)0.98
ED cost
 Total cost/pt. (2008–2015)800 (0–2082)843 (0–2526)966 (422–2965)0.46
 Median annual cost/pt.449 (0–871)449 (0–898)610 (409–968)0.36
MBS cost
 Total cost/pt. (2008–2015)17,017 (10,395–26,756)16,280 (9639–26,534)14,077 (8268–21,193)0.35
 Median annual cost/pt.2635 (1676–4000)2347 (1644-3935)2330 (1578–2968)0.12
Medication cost
 Total cost/pt. (2008–2015)1189 (646–8541)1395 (732–6007)1239 (928–7683)0.45
  1. Abbreviations: DU digital ulceration, MBS medicare benefits schedule, ED emergency department, CCB calcium channel blockers, ERAs endothelial receptor antagonists, PDE5 phosphodiesterase-5 inhibitors
  2. *DU severity was calculated based on the physician reported highest number of new DUs on examination at clinical review (mild 1–5 new DU, moderate 6–10, and severe > 10 new DU)