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Fig. 9 | Arthritis Research & Therapy

Fig. 9

From: Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis

Fig. 9

The expression of inflammation-associated proteins and mRNAs in Nrf2-knockdown SW982 cells treated with LPS for 24 h. a DHE staining (red fluorescence) was performed to evaluate the level of ROS. Representative images are shown from repeated experiments. Scale bar = 100 μm. b, c Representative images of Western blots depicting the expression levels of NLRP3 and Nrf2 in SW982 cells and the protein/GAPDH ratios as determined by the densitometric analysis of the Western blots. d Nrf2, HO-1, NLRP3, IL-1β, and IL-18 mRNA expression examined using qRT-PCR (n = 3, n.s.P > 0.05, *P < 0.05, **P < 0.01)

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